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Download Glioblastoma  State of the Art and Future Perspectives PDF
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Publisher : MDPI
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ISBN 10 : 9783039282609
Pages : 784 pages
Rating : 4.0/5 (392 users)
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Download or read book Glioblastoma State of the Art and Future Perspectives written by Ghazaleh Tabatabai and published by MDPI. This book was released on 2020-12-10 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glioblastoma is an aggressive incurable primary tumor of the central nervous system. Median overall survival is in the range of 1.5 years even in selected clinical trials populations. Many features contribute to this therapeutic challenge including high intratumoral and intertumoral heterogeneity, resistance to therapy, migration and invasion, immunosuppression. With the access of novel highthroughput technologies, significant progress has been made to understand molecular and immunological signatures underlying the pathology of glioblastoma. Clinical trial designs have shifted from investigating broad “one-for-all” treatment approaches to precision oncology designs. The collection of contributions in this book aim at providing researchers and clinicians an update on different aspects of glioblastoma, i.e. progress in basic, preclinical and clinical research.

Download Glioblastoma  State of the Art and Future Perspectives PDF
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ISBN 10 : 3039282611
Pages : 784 pages
Rating : 4.2/5 (826 users)
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Download or read book Glioblastoma State of the Art and Future Perspectives written by Ghazaleh Tabatabai and published by . This book was released on 2020 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glioblastoma is an aggressive incurable primary tumor of the central nervous system. Median overall survival is in the range of 1.5 years even in selected clinical trials populations. Many features contribute to this therapeutic challenge including high intratumoral and intertumoral heterogeneity, resistance to therapy, migration and invasion, immunosuppression. With the access of novel highthroughput technologies, significant progress has been made to understand molecular and immunological signatures underlying the pathology of glioblastoma. Clinical trial designs have shifted from investigating broad “one-for-all” treatment approaches to precision oncology designs. The collection of contributions in this book aim at providing researchers and clinicians an update on different aspects of glioblastoma, i.e. progress in basic, preclinical and clinical research.

Download Novel Small Molecule Agents in Overcoming Multidrug Resistance in Cancers PDF
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Publisher : Frontiers Media SA
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ISBN 10 : 9782889762354
Pages : pages
Rating : 4.8/5 (897 users)
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Download or read book Novel Small Molecule Agents in Overcoming Multidrug Resistance in Cancers written by Qingbin Cui and published by Frontiers Media SA. This book was released on 2022-05-30 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download Intraoperative Ultrasound in Brain Tumor Surgery  State Of The Art and Future Perspectives PDF
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Publisher : Frontiers Media SA
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ISBN 10 : 9782889719334
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Download or read book Intraoperative Ultrasound in Brain Tumor Surgery State Of The Art and Future Perspectives written by Massimiliano Del Bene and published by Frontiers Media SA. This book was released on 2021-12-20 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download Frontiers in Clinical Drug Research   Anti Cancer Agents  Volume 7 PDF
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Publisher : Bentham Science Publishers
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ISBN 10 : 9781681087764
Pages : 223 pages
Rating : 4.6/5 (81 users)
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Download or read book Frontiers in Clinical Drug Research Anti Cancer Agents Volume 7 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2021-07-07 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research - Anti-Cancer Agents is a book series intended for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for developing clinical trials and devising research plans in anti-cancer research. Reviews in each volume are written by experts in medical oncology and clinical trials research and compile the latest information available on special topics of interest to oncology and pharmaceutical chemistry researchers. The seventh volume of the book features reviews on these topics: · Essential oils and monoterpenes as potential anti-cancer agents · Drug delivery systems and emerging immunotherapeutic strategies for the treatment of glioblastoma · CTDNA in solid tumors · Cholesterol treatments (including Pitavastatin) and their potential in cancer treatment

Download Nanomedicine and Neuroprotection in Brain Diseases PDF
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Publisher : Elsevier
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ISBN 10 : 9780323901635
Pages : 442 pages
Rating : 4.3/5 (239 users)
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Download or read book Nanomedicine and Neuroprotection in Brain Diseases written by Hari Shanker Sharma and published by Elsevier. This book was released on 2021-09-22 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Progress in Brain Research series Updated release includes the latest information on the Neuropharmacology of Neuroprotection

Download Radiochemotherapy in Multimodal Cancer Therapy PDF
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Publisher : Frontiers Media SA
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ISBN 10 : 9782889745609
Pages : pages
Rating : 4.8/5 (897 users)
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Download or read book Radiochemotherapy in Multimodal Cancer Therapy written by Benjamin Frey and published by Frontiers Media SA. This book was released on 2022-03-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download Minimally Invasive Techniques for Neurosurgery PDF
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Publisher : Springer Science & Business Media
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ISBN 10 : 9783642587313
Pages : 303 pages
Rating : 4.6/5 (425 users)
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Download or read book Minimally Invasive Techniques for Neurosurgery written by Dieter Hellwig and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: A summary of all facets of this new and rapidly developing field in neurosurgery. Besides neuroendoscopy, the books main topics are neuronavigation, functional neurosurgery, radiosurgery, neurotransplantation, and molecular neurosurgery. Provides a thorough overview of the state of the art and future perspectives in minimally invasive neurosurgery.

Download The Cell Cycle in the Central Nervous System PDF
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Publisher : Springer Science & Business Media
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ISBN 10 : 9781597450218
Pages : 563 pages
Rating : 4.5/5 (974 users)
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Download or read book The Cell Cycle in the Central Nervous System written by Damir Janigro and published by Springer Science & Business Media. This book was released on 2008-01-23 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Cycle in the Central Nervous System overviews the changes in cell cycle as they relate to prenatal and post natal brain development, progression to neurological disease or tumor formation.Topics covered range from the cell cycle during the prenatal development of the mammalian central nervous system to future directions in postnatal neurogenesis through gene transfer, electrical stimulation, and stem cell introduction. Additional chapters examine the postnatal development of neurons and glia, the regulation of cell cycle in glia, and how that regulation may fail in pretumor conditions or following a nonneoplastic CNS response to injury. Highlights include treatments of the effects of deep brain stimulation on brain development and repair; the connection between the electrophysiological properties of neuroglia, cell cycle, and tumor progression; and the varied immunological responses and their regulation by cell cycle.

Download Repurposed Drugs Targeting Cancer Signaling Pathways  Dissecting New Mechanisms of Action Through in vitro and in vivo Analyses PDF
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Publisher : Frontiers Media SA
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ISBN 10 : 9782889717163
Pages : pages
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Download or read book Repurposed Drugs Targeting Cancer Signaling Pathways Dissecting New Mechanisms of Action Through in vitro and in vivo Analyses written by Alma D. Campos-Parra and published by Frontiers Media SA. This book was released on 2021-11-29 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download Gene Therapy in the CNS     Progress and Prospects for Novel Therapies PDF
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Publisher : Frontiers Media SA
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ISBN 10 : 9782889718528
Pages : pages
Rating : 4.8/5 (897 users)
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Download or read book Gene Therapy in the CNS Progress and Prospects for Novel Therapies written by Casper René Gøtzsche and published by Frontiers Media SA. This book was released on 2021-12-21 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download Cancer Stem Cells  Emerging Concepts and Future Perspectives in Translational Oncology PDF
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Publisher : Springer
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ISBN 10 : 9783319210308
Pages : 560 pages
Rating : 4.3/5 (192 users)
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Download or read book Cancer Stem Cells Emerging Concepts and Future Perspectives in Translational Oncology written by Sadegh Babashah and published by Springer. This book was released on 2015-11-12 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of cancer stem cells has great clinical implications. This is due to the fact that small subpopulations of these cells have been identified in a variety of neoplastic conditions ranging from solid tumors to liquid malignancies. Although there are some huge gaps in our current understanding of the role played by cancer stem cells in cancer biology, a growing body of evidence provides strong support for the principal functions of these cells in tumorigenesis. This has represented the potential of cancer stem cells in the development of novel and innovative tools for the treatment of metastatic tumors. This book aims to offer a broad framework for obtaining insight into the state-of-the-art knowledge on cancer stem cell biology and highlight the therapeutic implications of these cells in the future of clinical oncology.

Download Radiobiology of Glioblastoma PDF
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Publisher : Springer
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ISBN 10 : 9783319283050
Pages : 305 pages
Rating : 4.3/5 (192 users)
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Download or read book Radiobiology of Glioblastoma written by Luigi Pirtoli and published by Springer. This book was released on 2016-06-06 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text properly considers the most recent and relevant advances in molecular RB of GB, taking into account the related topics of pathobiology, and underscores the most promising translational perspectives from the preclinical to the clinical domain. Section I (From Bedside to Bench) discusses conditions associated with RT resistance of GB and the consequent RB hints, technology improvements intended to overcome RT-resistance of GB, mathematical modeling of RB parameters from clinical studies, the present impact of molecular prognostic factors in therapy of GB, and RT tolerance of normal brain. Section II (Preclinical Research and Pathobiology Topics) presents the traditional and mechanistic/molecular approaches to RB of GB, genetic and epigenetic studies on GB, issues of cell-death pathways, stem-like cells, invasiveness, tumor microenvironment, hypoxia, mi-RNA manipulations, and nanoparticle technology. Section III (Translational Perspectives) presents RB issues related to molecular profiling and classification of GB as frames of reference for clinical studies, translational perspectives of gene therapy, evolving protocols based on pre-clinical data and large data-bases and ontologic models. Radiobiology of Glioblastoma: Recent Advances and Related Pathobiology will be of great value to pathologists, medical oncologists, radiation oncologists as well as basic researchers and clinical investigators.

Download Large Animals as Models for Human Diseases PDF
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Publisher : Academic Press
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ISBN 10 : 9780323994422
Pages : 354 pages
Rating : 4.3/5 (239 users)
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Download or read book Large Animals as Models for Human Diseases written by Ya-Xiong Tao and published by Academic Press. This book was released on 2022-05-17 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Large Animals as Models for Human Diseases, Volume 189 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of important topics, including Sheep as a model for neuroendocrinology research, Relevance of dog as a model for urologic diseases, Relevance of lactocrine hypothesis to human maternal programming of development, Comparative aspects of embryo implantation, Pig as an animal model for obesity, Canine models of cancer, Bovine model for human ovarian diseases, Mutations in G protein-coupled receptors in large animals: Modeling human diseases, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Progress in Molecular Biology and Translational Science series Updated release includes the latest information on Large Animals as Models for Human Diseases

Download Purinergic Signaling 2020  the State of The Art Commented by the Members of the Italian Purine Club PDF
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Publisher : Frontiers Media SA
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ISBN 10 : 9782889715701
Pages : pages
Rating : 4.8/5 (897 users)
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Download or read book Purinergic Signaling 2020 the State of The Art Commented by the Members of the Italian Purine Club written by Francesco Caciagli and published by Frontiers Media SA. This book was released on 2021-10-29 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download Ionizing Radiation and Human Health  A Multifaceted Relationship PDF
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Publisher : Frontiers Media SA
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ISBN 10 : 9782889740000
Pages : pages
Rating : 4.8/5 (897 users)
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Download or read book Ionizing Radiation and Human Health A Multifaceted Relationship written by Lorenzo Manti and published by Frontiers Media SA. This book was released on 2022-01-07 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download Imaging of Brain Tumors  An Issue of Magnetic Resonance Imaging Clinics of North America  PDF
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Publisher : Elsevier Health Sciences
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ISBN 10 : 9780323459761
Pages : pages
Rating : 4.3/5 (234 users)
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Download or read book Imaging of Brain Tumors An Issue of Magnetic Resonance Imaging Clinics of North America written by Rivka R. Colen and published by Elsevier Health Sciences. This book was released on 2016-10-15 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of MRI Clinics of North America focuses on Imaging of Brain Tumors, and is edited by Dr. Rivka Colen. Articles will include: Multiparametric Imaging Analysis: MR Spectroscopy; Genomics and MicroRNAs in Glioma; Metabolomics and Hyperpolarization MRI in Brain Tumors; Imaging Genomics in Glioma; Radiomics and Big Data in Imaging; RANO Criteria and Clinical Endpoints; Gliomas: The New WHO Brain Tumor Pathological/Molecular Classification and Clinical and Radiographic Classifications; Liposomal Contrast Agents and Nanoparticles in Brain Tumor Imaging; Multiparametric Imaging Analysis: Perfusion, and more!