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Download Radiobiology of Glioblastoma PDF
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Publisher : Springer
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ISBN 10 : 9783319283050
Pages : 305 pages
Rating : 4.3/5 (192 users)
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Download or read book Radiobiology of Glioblastoma written by Luigi Pirtoli and published by Springer. This book was released on 2016-06-06 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text properly considers the most recent and relevant advances in molecular RB of GB, taking into account the related topics of pathobiology, and underscores the most promising translational perspectives from the preclinical to the clinical domain. Section I (From Bedside to Bench) discusses conditions associated with RT resistance of GB and the consequent RB hints, technology improvements intended to overcome RT-resistance of GB, mathematical modeling of RB parameters from clinical studies, the present impact of molecular prognostic factors in therapy of GB, and RT tolerance of normal brain. Section II (Preclinical Research and Pathobiology Topics) presents the traditional and mechanistic/molecular approaches to RB of GB, genetic and epigenetic studies on GB, issues of cell-death pathways, stem-like cells, invasiveness, tumor microenvironment, hypoxia, mi-RNA manipulations, and nanoparticle technology. Section III (Translational Perspectives) presents RB issues related to molecular profiling and classification of GB as frames of reference for clinical studies, translational perspectives of gene therapy, evolving protocols based on pre-clinical data and large data-bases and ontologic models. Radiobiology of Glioblastoma: Recent Advances and Related Pathobiology will be of great value to pathologists, medical oncologists, radiation oncologists as well as basic researchers and clinical investigators.

Download Advances in the Biology  Imaging and Therapies for Glioblastoma PDF
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Publisher : IntechOpen
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ISBN 10 : 9533072849
Pages : 436 pages
Rating : 4.0/5 (728 users)
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Download or read book Advances in the Biology Imaging and Therapies for Glioblastoma written by Clark Chen and published by IntechOpen. This book was released on 2011-11-09 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended for physicians and scientists with interest in glioblastoma biology, imaging and therapy. Select topics in DNA repair are presented here to demonstrate novel paradigms as they relate to therapeutic strategies. The book should serve as a supplementary text in courses and seminars as well as a general reference.

Download Glioma PDF
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Publisher : BoD – Books on Demand
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ISBN 10 : 9781789849530
Pages : 258 pages
Rating : 4.7/5 (898 users)
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Download or read book Glioma written by Ibrahim Omerhodzic and published by BoD – Books on Demand. This book was released on 2019-01-16 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past three decades have been marked with huge enthusiasm from scientists and professionals in an effort to find a cure for glioma disease. Methods to confirm the kinds and grades of glioma have taken a path from classical macro- to microscopic pathohystological confirmation of tumors, through morphological-histological, molecular, and genetic diagnosis. Surgically, progress was made possible with the development and use of technological aids, for example neuronavigation, cortical mapping, electrocorticography, neuromonitoring, functional and intraoperative MRI, magnetoencephalography, etc. Great hope was placed on the extension of tumor resection and popular supratotal resection. Significant progress has been made generally in glioma treatment with the use of modern radiotherapy and new chemotherapeutics. What do we want to see for the future? By way of stem cells, a specific medicine will be produced, individualized for the particular patient, and by using a microcapsule it will be implanted into the brain zone affected by the tumor by way of robot surgery and injection needle. This is not at all an unrealistic expectation in the next decade or two.

Download Epidemiology of Brain and Spinal Tumors PDF
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Publisher : Academic Press
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ISBN 10 : 9780128217559
Pages : 552 pages
Rating : 4.1/5 (282 users)
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Download or read book Epidemiology of Brain and Spinal Tumors written by Jahangir Moini and published by Academic Press. This book was released on 2021-04-16 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors. Provides the most up-to-date information surrounding the epidemiology, biology and imaging techniques for brain and spinal tumors, including CT, MRI, PET, and others Includes full color figures, photos, tables, graphs and radioimaging Contains information that will be valuable to anyone interested in the field of neurooncology and the treatment of patients with brain and spinal tumors Serves as a source of background information for basic scientists and pharmaceutical researchers who have an interest in imaging and treatment

Download Brachytherapy  Second Edition PDF
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Publisher : Springer Publishing Company
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ISBN 10 : 9781617052613
Pages : 568 pages
Rating : 4.6/5 (17 users)
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Download or read book Brachytherapy Second Edition written by Phillip M. Devlin, MD, FACR and published by Springer Publishing Company. This book was released on 2015-10-14 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only comprehensive guide to the latest knowledge and techniques in brachytherapy Since the first edition was published in 2006, Phillip M. Devlinís Brachytherapy has been acknowledged as the essential book on the practice. Inthis updated new edition, all chapters covering cancer sites have been significantly revised. Organized for specialists in several fields, Brachytherapy contains site-specific chapters that discuss how the evolving role of advanced image guidance has demonstrated greater efficacy and less toxicity. Clinical vignettes with images now accompany all site-specific chapters. The chapter on prostate brachytherapy has been expanded to include other indications in the genitourinary system, and there are two entirely new chaptersóone chronicling the history of brachytherapy and the other detailing the emergence of skin brachytherapy. Dr. Devlin, a leading world authority on brachytherapy, has assembled other leaders in the field from world-renowned radiation oncology programs to enrichthis comprehensive text. From new data on medical outcomes to the costs and benefits of running a brachytherapy practice, Brachytherapy, Second Edition is the first and last word on what still is considered the most conformal radiotherapy technique in the field. In the new edition: Over 300 images accompany the chapter text and clinical vignettes Essential tables and spreadsheets enhance the chapter on running a brachytherapy practice Ten years of technological advancements are assimilated and reviewed in each site-specific chapter Includes access to the fully-searchable downloadable ebook From the Foreword: ìAs education is essential to advance awareness of and proficiency in the full spectrum of brachytherapy applications, the appearance of the second edition of this highly regarded text is both a timely and most welcome event. The distinguished list of contributors to this work reads like a veritable ìWhoís Whoî of international brachytherapy expertise making this an indispensable resource for students and practitioners of this complex and challenging modality[Ö]A particularly welcome feature is the clinical vignettes at the close of every chapter that bring seemingly remote concepts to life in real world practical applications[Ö]With the second edition of Brachytherapy: Applications and Techniques, Dr. Devlin and colleagues give us a text that instills a profound appreciation for the critical value of this essential modality. This book makes it clear that brachytherapy not only works, it is an irreplaceable component of contemporary cancer care.î --David Wazer, MD, FACRO, FACR, FASTRO, Professor and Chairman, Departments of Radiation Oncology, Alpert Medical School of Brown University, Providence, RI

Download Advances in the Biology  Imaging and Therapies for Glioblastoma PDF
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Publisher : BoD – Books on Demand
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ISBN 10 : 9789533072845
Pages : 436 pages
Rating : 4.5/5 (33 users)
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Download or read book Advances in the Biology Imaging and Therapies for Glioblastoma written by Clark Chen and published by BoD – Books on Demand. This book was released on 2011-11-09 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended for physicians and scientists with interest in glioblastoma biology, imaging and therapy. Select topics in DNA repair are presented here to demonstrate novel paradigms as they relate to therapeutic strategies. The book should serve as a supplementary text in courses and seminars as well as a general reference.

Download Radiobiology Self Assessment Guide PDF
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Publisher : Springer Publishing Company
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ISBN 10 : 9781617052910
Pages : 520 pages
Rating : 4.6/5 (17 users)
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Download or read book Radiobiology Self Assessment Guide written by Jennifer Yu, MD, PhD and published by Springer Publishing Company. This book was released on 2016-11-03 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiobiology Self-Assessment Guide--a companion to the Radiation Oncology Self-Assessment Guide and Physics in Radiation Oncology Self-Assessment Guide--is a comprehensive review for practitioners of radiation oncology looking to enhance their knowledge of radiobiology. It covers in depth the principles of radiobiology as applied to radiation oncology along with their clinical applications. To foster retention of key concepts and data, the resource utilizes a user-friendly "flash card" question and answer format with over 700 questions. The questions are supported by detailed answers and rationales along with reference citations for source information. The guide is comprised of 29 chapters and cover topics commonly found on the radiation and cancer biology portion of the radiation oncology board examination. Aspects of basic radiobiology covered include fundamentals such as cell cycle, cell survival curves and interactions of radiation with matter, and acute and long-term sequelae of radiation. Modern concepts such as immunotherapy, radiogenomics, and normal and cancer stem cells are also included. Focused and authoritative, this must-have review provides the expertise of faculty from the Department of Radiation Oncology at the Cleveland Clinic Taussig Cancer Institute and Lerner Research Institute. Key Features: Provides a comprehensive study guide for the Radiation and Cancer Biology portion to the Radiation Oncology Board Exam Includes more than 700 questions with detailed answers and rationales on flip pages for easy, flash card-like review Includes essential review of cancer biology concepts such as immunotherapy, stem cells, gene therapy, chemotherapy and targeted agents Content provided by a vast array of contributors, including attending radiation oncology physicians, physicists, and radiation oncology residents

Download Targets of Cancer Diagnosis and Treatment PDF
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Publisher : Springer Nature
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ISBN 10 : 9783031039942
Pages : pages
Rating : 4.0/5 (31 users)
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Download or read book Targets of Cancer Diagnosis and Treatment written by Christian Stock and published by Springer Nature. This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download Malignant Gliomas  RMR V3 I2 PDF
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Publisher : Demos Medical Publishing
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ISBN 10 : 9781617051487
Pages : 252 pages
Rating : 4.6/5 (17 users)
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Download or read book Malignant Gliomas RMR V3 I2 written by and published by Demos Medical Publishing. This book was released on 2012-10-09 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiation Medicine Rounds is a trinary, hard cover periodical designed to provide an up-to-date review of a dedicated radiation medicine topic of interest to clinicians and scientists who are involved in the care of patients receiving radiotherapy. It is intended to serve as both a reference and instructional tool for students, housestaff, fellows, practicing clinicians, medical physicists, cancer biologists, radiobiologists, and interdisciplinary colleagues throughout the oncology spectrum. This issue of Radiation Medicine Rounds discusses the more salient topics surrounding the role of radiation therapy for malignant gliomas. The specialty of radiation therapy has increased in complexity over the years, yet as technology improves, the goal of improving outcomes while decreasing toxicity remains critical. Malignant gliomas remain among the most devastating of all malignancies, yet as conventional treatments (surgery, radiation, and chemotherapy) have become optimized overall survival has improved. The underlying molecular and genetic mechanisms of these tumors are becoming better understood, with one of the most important realizations being that histopathologically identical malignant gliomas often demonstrate very distinct clinical behaviors. Malignant Gliomas provides the practitioner with a current overview of best practices, recent research, and future directions in the management of this complex and challenging cancer.

Download Modern Management of High Grade Glioma  Part I  An Issue of Neurosurgery Clinics   E Book PDF
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Publisher : Elsevier Health Sciences
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ISBN 10 : 9781455744183
Pages : 174 pages
Rating : 4.4/5 (557 users)
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Download or read book Modern Management of High Grade Glioma Part I An Issue of Neurosurgery Clinics E Book written by Isaac Yang and published by Elsevier Health Sciences. This book was released on 2012-04-28 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts to highlight the latest updates on various forms of management of high grade glioma. Some of the articles included in this issue focus on Extent of Resection for Glioblastoma; Role of adjuvant radiation therapy; Survival benefit of the Temozolomide protocol; Alternative chemotherapeutic agents; The role of avastin; Radiology; Pseuodprogression and Treatment effect; Pathology; Medical Management; Management of insular gliomas; Use of motor mapping; GBM treatment with clinical trials for surgical resection; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Future role of CED for GBM treatment; Application of a vault nanoparticle therapy for GBM therapy; Management of high grade gliomas in pediatric populations; Targeting Glioma Stem Like Cells with a focus on CD 133; and Potential Role for STAT3 inhibitors in glioblastoma.

Download Basic Clinical Radiobiology Fourth Edition PDF
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Publisher : CRC Press
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ISBN 10 : 9780340929667
Pages : 375 pages
Rating : 4.3/5 (49 users)
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Download or read book Basic Clinical Radiobiology Fourth Edition written by Michael C. Joiner and published by CRC Press. This book was released on 2009-03-27 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise but comprehensive textbook sets out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics and radiation technology. Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, the fourth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer. New topics for the fourth edition include chapters on the mechanisms of cell death, biological response modifiers, and biological image guided radiotherapy, with major revisions to sections on the molecular basis of the radiation response, tumour hypoxia and the dose-rate effect. A variety of new authors have contributed to this revision, who, together with the new Editorial team, have used their significant international teaching experience to ensure the content remains clear and comprehensive, and as valuable to the trainee as it is to the established radiation oncologist. With the fourth edition we will see the most radical change so far - as Professor Gordon Steel has retired as Editor and has been replaced by Bert van der Kogel, the current current course director for the above-mentioned course, plus Michael Joiner, who is the head of the Radiation Biology Program at the Wayne State University and is the Associate Editor of the International Journal of Radiation Biology.

Download Radiobiology for the Radiologist PDF
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Publisher : Lippincott Williams & Wilkins
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ISBN 10 : 0781741513
Pages : 572 pages
Rating : 4.7/5 (415 users)
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Download or read book Radiobiology for the Radiologist written by Eric J. Hall and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: The updated Sixth Edition of this popular text will remain the first choice for those who need current, clinically relevant information on how radiation affects the human body. Written by practicing, active radiobiologists, the book brings together basic laboratory research and practical, clinical applications. The easy-to-read text and informative illustrations ensure comprehension, and summaries at the end of each chapter facilitate quick review. The first section covers topics applicable to diagnostic radiology, nuclear medicine, and radiation oncology; the second section offers material specifically for radiation oncologists. This edition includes new material about doses and risks in interventional radiology and cardiology.

Download Glioblastoma Resistance to Chemotherapy  Molecular Mechanisms and Innovative Reversal Strategies PDF
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Publisher : Academic Press
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ISBN 10 : 9780128215685
Pages : 828 pages
Rating : 4.1/5 (282 users)
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Download or read book Glioblastoma Resistance to Chemotherapy Molecular Mechanisms and Innovative Reversal Strategies written by Ramasamy Paulmurugan and published by Academic Press. This book was released on 2021-06-25 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field. Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood. Provides comprehensive, core knowledge related to the entire discipline of glioblastoma chemoresistance, from its many etiological mechanisms, to specific strategies to reverse resistance Presents current information from an international team of experts on the basic science, pre-clinical research, and clinical management of glioblastoma chemoresistance Discusses molecular and cellular mechanisms behind therapy resistant glioblastoma cells, as well as the therapeutic strategies available to counter this resistance

Download Targeted Radionuclide Therapy PDF
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Publisher : Lippincott Williams & Wilkins
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ISBN 10 : 9781451153262
Pages : 608 pages
Rating : 4.4/5 (511 users)
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Download or read book Targeted Radionuclide Therapy written by Tod W. Speer and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.

Download Neutron Capture Therapy PDF
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Publisher : Springer Science & Business Media
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ISBN 10 : 9783642313349
Pages : 554 pages
Rating : 4.6/5 (423 users)
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Download or read book Neutron Capture Therapy written by Wolfgang A.G. Sauerwein and published by Springer Science & Business Media. This book was released on 2012-11-05 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neutron capture therapy (NCT) is based on the ability of the non-radioactive isotope boron-10 to capture thermal neutrons with very high probability and immediately to release heavy particles with a path length of one cell diameter, which in principle allows for tumor cell-selective high-LET particle radiotherapy. This book provides a comprehensive summary of the progress made in NCT in recent years. Individual sections cover all important aspects, including neutron sources, boron chemistry, drugs for NCT, dosimetry, and radiation biology. The use of NCT in a variety of malignancies and also some non-malignant diseases is extensively discussed. NCT is clearly shown to be a promising modality at the threshold of wider clinical application. All of the chapters are written by experienced specialists in language that will be readily understood by all participating disciplines.

Download Handbuch der medizinischen Radiologie  T  1  Radiation theory of malignant tumors PDF
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ISBN 10 : UOM:39015007085908
Pages : 556 pages
Rating : 4.3/5 (91 users)
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Download or read book Handbuch der medizinischen Radiologie T 1 Radiation theory of malignant tumors written by Olle Gunnar Anton Olsson and published by . This book was released on 1985 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: