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Download Targeted Therapies for Glioblastoma  A Critical Appraisal PDF
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Publisher : Frontiers Media SA
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ISBN 10 : 9782889633531
Pages : pages
Rating : 4.8/5 (896 users)
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Download or read book Targeted Therapies for Glioblastoma A Critical Appraisal written by Shiv K. Gupta and published by Frontiers Media SA. This book was released on 2020-01-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download Glioblastoma  Part II  Molecular Targets and Clinical Trials  An Issue of Neurosurgery Clinics of North America PDF
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Publisher : Elsevier Health Sciences
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ISBN 10 : 9780323813068
Pages : 240 pages
Rating : 4.3/5 (238 users)
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Download or read book Glioblastoma Part II Molecular Targets and Clinical Trials An Issue of Neurosurgery Clinics of North America written by Linda M. Liau and published by Elsevier Health Sciences. This book was released on 2021-04-08 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Neurosurgery Clinics, guest edited by Dr. Linda M. Liau, is dedicated to Glioblastoma: Molecular and Clinical Trials. This issue is one of four selected each year by the series consulting editors, Drs. Russell R. Lonser and Daniel K. Resnick. Topics will include—but are not limited to—Pathology & Molecular Markers, Cellular States & Genetic Diversity in Glioblastoma, Mismatch Repair in Glioblastoma Resistance, Genetic Susceptibility in Brain Cancer, Pediatric Gliomas: Molecular Landscape & Emerging Targets, Molecularly Targeted Clinical Trials, Novel Radiation Sensitizers, Immunotherapy Checkpoint Inhibitors, Brain Tumor Vaccines, CAR T Cells, Oncolytic Virotherapy, Targeting Cancer Stem Cells, Therapeutic Delivery to CNS, Theranostics: Dual Modality PET Tracers, and Neuroimaging & Novel Response Assessments.

Download New Targeting in The Reversal of Resistant Glioblastomas PDF
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Publisher : Academic Press
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ISBN 10 : 9780128232767
Pages : 202 pages
Rating : 4.1/5 (282 users)
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Download or read book New Targeting in The Reversal of Resistant Glioblastomas written by Ali Syed Arbab and published by Academic Press. This book was released on 2021-03-05 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Targeting in The Reversal of Resistant Glioblastomas discusses alternative treatment strategies that not only target tumor cells but also target the tumor microenvironment, metabolic pathways and interaction of cytokines in tumor cells. The current treatment for primary and recurrent glioblastomas is failing because clinicians are not considering the effect of bone marrow derived cells to the development of resistance to clinically practiced therapies. This book helps readers rethink treatment strategies to successfully fight glioblastomas. It is a valuable resource for cancer researchers, clinicians, graduate students and other members of the biomedical field. Explains the effect of bone marrow derived cells on the development of resistance to clinically practiced therapies Provides information on the availability of alternate therapies for recurrent glioblastoma when standard practices have failed Discusses targeting tumor microenvironment using available FDA approved drugs as an alternative treatment strategy for glioblastoma

Download Advances and Challenges in Pharmaceutical Technology PDF
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Publisher : Academic Press
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ISBN 10 : 9780128203002
Pages : 568 pages
Rating : 4.1/5 (282 users)
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Download or read book Advances and Challenges in Pharmaceutical Technology written by Amit Kumar Nayak and published by Academic Press. This book was released on 2021-02-09 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances and Challenges in Pharmaceutical Technology: Materials, Process Development and Drug Delivery Strategies examines recent advancements in pharmaceutical technology. The book discusses common formulation strategies, including the use of tools for statistical formulation optimization, Quality by design (QbD), process analytical technology, and the uses of various pharmaceutical biomaterials, including natural polymers, synthetic polymers, modified natural polymers, bioceramics, and other bioinorganics. In addition, the book covers rapid advancements in the field by providing a thorough understanding of pharmaceutical processes, formulation developments, explorations, and exploitation of various pharmaceutical biomaterials to formulate pharmaceutical dosage forms. Provides extensive information and analysis on recent advancements in the field of pharmaceutical technology Includes contributions from global leaders and experts in academia, industry and regulatory agencies Uses high quality illustrations, flow charts and tables to explain concepts and text to readers, along with practical examples and research case studies

Download Role of Radiotherapy in the Era of Targeted Therapy and Precision Oncology PDF
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Publisher : Frontiers Media SA
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ISBN 10 : 9782889742684
Pages : pages
Rating : 4.8/5 (897 users)
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Download or read book Role of Radiotherapy in the Era of Targeted Therapy and Precision Oncology written by Kevin X. Liu and published by Frontiers Media SA. This book was released on 2022-02-03 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download Glioblastoma  State of the Art and Future Perspectives PDF
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Publisher : MDPI
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ISBN 10 : 9783039282609
Pages : 784 pages
Rating : 4.0/5 (392 users)
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Download or read book Glioblastoma State of the Art and Future Perspectives written by Ghazaleh Tabatabai and published by MDPI. This book was released on 2020-12-10 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glioblastoma is an aggressive incurable primary tumor of the central nervous system. Median overall survival is in the range of 1.5 years even in selected clinical trials populations. Many features contribute to this therapeutic challenge including high intratumoral and intertumoral heterogeneity, resistance to therapy, migration and invasion, immunosuppression. With the access of novel highthroughput technologies, significant progress has been made to understand molecular and immunological signatures underlying the pathology of glioblastoma. Clinical trial designs have shifted from investigating broad “one-for-all” treatment approaches to precision oncology designs. The collection of contributions in this book aim at providing researchers and clinicians an update on different aspects of glioblastoma, i.e. progress in basic, preclinical and clinical research.

Download Targeted Radionuclide Therapy PDF
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Publisher : Lippincott Williams & Wilkins
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ISBN 10 : 9781451153262
Pages : 608 pages
Rating : 4.4/5 (511 users)
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Download or read book Targeted Radionuclide Therapy written by Tod W. Speer and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.

Download The Textbook of Nanoneuroscience and Nanoneurosurgery PDF
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Publisher : CRC Press
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ISBN 10 : 9781439849422
Pages : 602 pages
Rating : 4.4/5 (398 users)
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Download or read book The Textbook of Nanoneuroscience and Nanoneurosurgery written by Babak Kateb and published by CRC Press. This book was released on 2013-07-25 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoneuroscience, nanoneurosurgery, and nanobioelectronics have the potential to revolutionize medicine and improve the prevention, diagnosis, and treatment of neurological disorders over the next 10-20 years. The Textbook of Nanoneuroscience and Nanoneurosurgery presents a state-of-the-art review of the field, providing current information about n

Download Adverse Events and Oncotargeted Kinase Inhibitors PDF
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Publisher : Academic Press
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ISBN 10 : 9780128094457
Pages : 736 pages
Rating : 4.1/5 (28 users)
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Download or read book Adverse Events and Oncotargeted Kinase Inhibitors written by Giuseppe Tridente and published by Academic Press. This book was released on 2017-05-08 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adverse Events and Oncotargeted Kinase Inhibitors gathers and evaluates data on adverse events associated with tyrosine kinase inhibitors (TKIs), a powerful anti-tumor drug class that has recently been introduced for human therapy. This book compiles a comprehensive safety profile of each TKI from experiences in official therapeutic indications, also exploring off-label exploratory investigations and postmarketing pharmaceutical surveillance databases. A brief history of each drug’s development and submission is provided, along with a more detailed analysis of the mechanism(s) of action involved in therapeutic activity or related to the insurgence of specific adverse events. Early chapters focus on general characteristics of TKIs, typology, and classification of adverse events, while the final chapters analyze TKIs as AE inducers and classes of AEs by system or organ involvement. This comprehensive resource compiles and critically reviews all of the relevant safety data for this class of drugs, with the goal of improving the understanding of pathogenesis and facilitating the prevention, monitoring, and management of these adverse events. Offers a unique and comprehensive publication on the adverse events associated with a new and fast-growing class of medicines Provides a systematic analysis of adverse events aimed at better prevention through understanding and offering insights for the development of safer drugs Uses practical guidelines to establish a leading reference on this class of drugs for educators, researchers, drug developers, clinicians, safety professionals, and more

Download Nanotechnology for Cancer Therapy PDF
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Publisher : CRC Press
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ISBN 10 : 9781420006636
Pages : 840 pages
Rating : 4.4/5 (2 users)
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Download or read book Nanotechnology for Cancer Therapy written by Mansoor M. Amiji and published by CRC Press. This book was released on 2006-12-19 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: While simultaneous breakthroughs occurring in molecular biology and nanoscience/technology will ultimately revolutionize all of medicine, it is with our efforts to prevent, diagnose, and treat cancer that many of the most dramatic advances will occur. In support of this potential, the U.S. National Cancer Institute (NCI) established the Alliance fo

Download Phosphoinositide 3 kinase in Health and Disease PDF
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Publisher : Springer Science & Business Media
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ISBN 10 : 9783642148163
Pages : 306 pages
Rating : 4.6/5 (421 users)
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Download or read book Phosphoinositide 3 kinase in Health and Disease written by Christian Rommel and published by Springer Science & Business Media. This book was released on 2010-10-17 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: PI3K has become a very intense area of research, with over 2000 publications on PI3K in PubMed for 2009 alone. The expectations for a therapeutic impact of intervention with PI3K activity are high, and progress in the clinical arena is being monitored by many. However, targeted therapies almost invariably encounter roadblocks, often exposing unresolved questions in the basic understanding of the target

Download Journey to the Center of the Brain  Cell Physiology and Intercellular Communication In White Matter PDF
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Publisher : Frontiers Media SA
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ISBN 10 : 9782889748525
Pages : pages
Rating : 4.8/5 (897 users)
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Download or read book Journey to the Center of the Brain Cell Physiology and Intercellular Communication In White Matter written by Maria Kukley and published by Frontiers Media SA. This book was released on 2022-04-05 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download Principles of Neuro Oncology PDF
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Publisher : Springer Nature
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ISBN 10 : 9783030548797
Pages : 982 pages
Rating : 4.0/5 (35 users)
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Download or read book Principles of Neuro Oncology written by Alejandro Monroy-Sosa and published by Springer Nature. This book was released on 2020-12-23 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the management of brain and skull base tumors. It features detailed insight into the intrinsic molecular biology, anatomical foundation, radiological planning, surgical execution, and the novel therapeutics that guide today’s treatment regimens. The first section features concepts related to the epidemiology and pathological basis of disease processes, including relevant cellular and molecular biology. In the second section, integral anatomical foundations and principles are covered including microsurgical anatomy of the cerebrum, white matter tracts, ventricles, brainstem, skull base, advancements in radiological imaging, and cognitive examinations. Surgical approaches and how to execute these procedures are then subsequently discussed in the third part of the work. Principles of Neuro-Oncology: Brain & Skull Base is a practically applicable guide to the latest treatment techniques available to treat these patients. Therefore, it is an indispensable resource for all physicians who utilize these methodologies in their day-to-day practice.

Download Gliomas PDF
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Publisher : Academic Press
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ISBN 10 : 9780128030073
Pages : 464 pages
Rating : 4.1/5 (28 users)
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Download or read book Gliomas written by and published by Academic Press. This book was released on 2016-03-02 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers’ knowledge of gliomas continues to advance rapidly at both the basic and translational levels, and Gliomas provides a thorough overview of the evolving fields of tumor biology and clinical medicine as they relate to our understanding of brain tumors. Gliomas reviews the current paradigms that underlie these fields, beginning with the molecular epidemiology of glioma susceptibility and prognosis through population-based science and genome-wide association studies. The book’s discussion of imaging modalities extends beyond advances in anatomical imaging to include metabolic and physiological studies. This work provides thorough discussion of the clinical view of tumors, ranging from the presentation of the patient to surgical management, and covers all therapeutic options for patient care, including chemotherapy, targeted molecular therapies, immunotherapies, and even personalized approaches to impact the set of lesions. Additionally, the book discusses radiotherapy with regard to the many options available to treat patients using myriad fractionated techniques with various sources. Finally, Gliomas reviews issues specific to the quality of life for patients, and techniques for maximizing the effect of caregivers. Edited and authored by premier researchers from around the world, Gliomas is a comprehensive reference for clinicians and researchers seeking the most up-to-date information on gliomas, and a guide to the best ways to effectively manage glioma patients and their care. Synthesizes widely dispersed information on the management of gliomas into one comprehensive resource Chapters written by international authors who are preeminent researchers in the field Fully explores the therapeutic options for patient care, from chemotherapy to radiotherapy to personalized approaches

Download Management of CNS Tumors PDF
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Publisher : BoD – Books on Demand
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ISBN 10 : 9789533076461
Pages : 476 pages
Rating : 4.5/5 (33 users)
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Download or read book Management of CNS Tumors written by Miklos Garami and published by BoD – Books on Demand. This book was released on 2011-09-22 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management of CNS Tumors is a selected review of Central Nervous System (CNS) tumors with particular emphasis on pathological classification and complex treatment algorithms for each common tumor type. Additional detailed information is provided on selected CNS tumor associated disorders.

Download Pediatric CNS Tumors PDF
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Publisher : Springer
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ISBN 10 : 9783319307893
Pages : 387 pages
Rating : 4.3/5 (193 users)
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Download or read book Pediatric CNS Tumors written by Nalin Gupta and published by Springer. This book was released on 2016-09-21 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric CNS Tumors is a detailed review of childhood brain tumors that offers a biologically based perspective on their management. For each tumor type, epidemiology, pathological features, clinical presentation, diagnosis, and treatment are discussed. Particular emphasis is placed on the provision of treatment algorithms that reflect current best practice, and controversies and therapeutic agents under development are also addressed. The closing chapters consider many of the diagnostic and treatment modalities common to all tumors, with special attention to experimental and emerging techniques. This third edition of the book has been thoroughly revised and updated to take into account the latest advances in knowledge and treatment.

Download Glioblastomas  New Insights for the Healthcare Professional  2013 Edition PDF
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Publisher : ScholarlyEditions
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ISBN 10 : 9781481652735
Pages : 373 pages
Rating : 4.4/5 (816 users)
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Download or read book Glioblastomas New Insights for the Healthcare Professional 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glioblastomas: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Glioblastomas: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Glioblastomas: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.